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KMID : 0869220210250010049
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Journal of Korean Geriatric Psychiatry
2021 Volume.25 No. 1 p.49 ~ p.55
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Analysis of Correlation Between Cognitive Function and Depressive Symptoms of the Elderly in Community
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Cho Hyun
Byun Gi-Hwan
Kwon Sung-Ok
Han Ji-Won
Bae Jong-Bin
Yang Hee-Won
Lim Eun-Ji
Kim Ki-Woong
Kwak Kyung-Phil
Kim Bong-Jo
Kim Shin-Gyeom
Kim Jeong-Lan
Moon Seok-Woo
Park Joon-Hyuk
Yoon Jong-Chul
Lee Dong-Young
Lee Dong-Woo
Lee Seok-Bum
Lee Jung-Jae
Jeong Hyun-Ghang
Kim Tae-Hui
Ryu Seung-Ho
Jhoo Jin-Hyeong
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Abstract
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Objective: The aim of this study was to reveal the association between the depressive symptom and cognitive function of participants with normal cognitive function, mild cognitive impairment (MCI), and dementia in a large-scale community elderly cohort.
Methods: A total of 6,338 elderly participants who participated in the Korean Longitudinal Study on Cognitive Aging and Dementia (KLOSCAD) from November 2010 to October 2012 were evaluated through cross-sectional analysis. Cognitive evaluation was conducted with Korean Version of Mini Mental Status Exam for Dementia Screening (MMSE-DS) and Consortium to Establish a Registry for Alzheimer’s Disease Assessment Packet (CERAD) neuropsychological tests, and depressive symptoms were evaluated with Revised Korean Version of the Geriatric Depression Scale (GDS-KR).
Results: 4,352 normal cognitive elderly participants, 1,748 MCI and 238 dementia participants were enrolled in the study. Correlation analysis showed a significant negative correlation between MMSE-DS and GDS-KR in the normal elderly group and participants with MCI, but not in dementia participants. This was the same in the correlation between CERAD-TS (total score) and GDSKR score.
Conclusion: This study found that worse cognitive function in the community cohort worsened depressive symptoms in groups with normal and MCI, but no significant correlation was observed in patients with dementia.
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KEYWORD
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Depression, Mild cognitive impairment, Dementia, Community, Elderly
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